ALDH1A1/2/3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-13801-60, E-AB-13801-120, E-AB-13801-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ALDH1A1/ALDH1A2/ALDH1A3

Target Synonym: ALDC; ALDH1; PUMB1; ALDH11; RALDH1; ALDH-E1; RALDH2; RALDH2-T; RALDH(II); ALDH6; RALDH3; ALDH1A6

Research Areas: Cancer, Neuroscience, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P00352,O94788,P47895

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Concentration: 0.4 mg/mL

Immunogen: Recombinant protein of human ALDH1A1/ALDH1A2/ALDH1A3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:150

Calculated MW: 57kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only