EMC8 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-14013-60, E-AB-14013-120, E-AB-14013-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: EMC8

Target Synonym: C16orf2; C16orf4; COX4 neighbor; COX4; neighbor of; COX4AL; Cox4nb; CX4NB; ER membrane protein complex subunit 8; FAM158B; family with sequence similarity 158; member B; Neighbor of COX4; NOC4; Protein FAM158B

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O43402

Background: The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration: 0.8 mg/mL

Immunogen: Recombinant protein of human EMC8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 24kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only