Na+ CP type VIIα Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27565-50, RA27565-100

Citations, Manuals and MSDS Available upon request.

Background: sodium voltage-gated channel alpha subunit 7 (SCN7A) Homo sapiens This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: SCN7A; SCN6A; Sodium channel protein type 7 subunit alpha; Putative voltage-gated sodium channel subunit alpha Nax; Sodium channel protein cardiac and skeletal muscle subunit alpha; Sodium channel protein type VII subunit alpha

Applications: WB; IF/ICC; ELISA

Species Cross-Reactivity: Human; Monkey

GeneID (Human): 6332

Protein MW (KDa): 200

SWISS: Q01118

Source: Rabbit

Research Use Only