ATL2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES18200-50, ES18200-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009],

Alternate Name: ADAMTS-like protein 2 (ADAMTSL-2)

Source: Rabbit

Applications: WB

Dilution: WB 1:500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human ATL2 AA range: 194-244

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 105kD

Human Gene ID: 9719

Human SWISS Prot NO: Q86TH1

Subcellular Location: Secreted

Research Use Only